Cultivation Process of Blazei-MRL™
Mycology Research Laboratories Ltd.´s Agaricus blazei, is grown on a sterilised (autoclaved) substrate under ISO 22000:2018 standards in the EU.
This cultivation process ensures the powder complies with the EU regulation 1881/2006 for contamination of pesticides and heavy metals. The cultivation system is proprietary, allowing for standardised production of Agaricus blazei.
MRL mushrooms biomass offers a mixture of many co-operating and co-related healthful bioavailable ingredients prepared by nature itself – it is thus a truly pure natural product.
After cultivation the Agaricus blazei is then manufactured in the Netherlands into 500 mg tablets and in various powder forms to FSSC 22000 (Version 4.1) standards.
Veterinary products are manufactured under veterinary registration number (NL217476).
Moreover, all powder presentations are produced and manufactured in accordance with both EU and UK organic standards.
Chemical and Biological Properties *
Agaricus blazei* Content per gram of biomass (in the absence of Proteolytic Enzymes)
| Cytochrome P-450 | 0.45 nmoles |
| Cytochrome P-450 reductase | 8.90 mU |
| Xylanase | 12.80 U |
| Celulase | 0.38 U |
| Amyloglucosidase | 0.80 U |
| Protein bound polysacharides | 87.6 mg |
| Proteins | 5.16 mg |
| Reducing sugars | 20.38 mg |
| Superoxide dismutase (SOD) | 275.0 U |
| Protease | 11.2 U |
Blazei-MRL –Enzyme activity (U/500 mg Biomass)**
| Superoxide dismutase (SOD) | 143.5 103 U |
| NADPH (Cyt. "P-450" reductase) | 7,500 uM |
| GSH Reductase | 510.0 U |
| Catalase | 996.5 U |
| Laccase | N/A |
| Tyrosinase | 6849 U |
| Peroxidase | N/A |
* Agaricus blazei supplied by Mycology Research Laboratories Ltd.
** Cornelius C. e tal “ Comparative Enzyme Analysis of Polyporus umbellatus, Agaricus blazei, Pleurotus osteratus and Hericium erinaceus” pp 5, Clinical Journal of Mycology, 7;2009 Vol II.